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[Effect of L-lysine-alpha-oxidase on the cell cycle kinetics of cultured Burkitt's lymphoma cells].
- Source :
-
Eksperimental'naia onkologiia [Eksp Onkol] 1985; Vol. 7 (6), pp. 42-4. - Publication Year :
- 1985
-
Abstract
- L-lysine-alpha-oxidase from Trichoderma sp. fungi inhibits the synthesis of DNA, RNA and protein in cultivated cells of the Burkitt lymphoma (strain P3HRj) in vitro, which results in the blocking of the cells' transfer from phase S to phase G2/M of the mitotic cycle.
- Subjects :
- Burkitt Lymphoma metabolism
Cell Cycle drug effects
Cells, Cultured
DNA, Neoplasm biosynthesis
Dose-Response Relationship, Drug
Drug Evaluation, Preclinical
Humans
Neoplasm Proteins biosynthesis
RNA, Neoplasm biosynthesis
Time Factors
Trichoderma enzymology
Amino Acid Oxidoreductases toxicity
Burkitt Lymphoma pathology
Subjects
Details
- Language :
- Russian
- ISSN :
- 0204-3564
- Volume :
- 7
- Issue :
- 6
- Database :
- MEDLINE
- Journal :
- Eksperimental'naia onkologiia
- Publication Type :
- Academic Journal
- Accession number :
- 4085397