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Pituitary tumors in mice after prolonged feeding of synthetic progestins.

Authors :
Poel WE
Source :
Science (New York, N.Y.) [Science] 1966 Oct 21; Vol. 154 (3747), pp. 402-3.
Publication Year :
1966

Abstract

An enhanced development of pituitary tumors was observed in virgin female mice of the C57 Leaden strain following repeated oral administration of synthetic progestins. This finding appears to parallel the co-carcinogenic enhancement of mammary tumor development elicited in C3H mice treated repeatedly with progesterone.

Details

Language :
English
ISSN :
0036-8075
Volume :
154
Issue :
3747
Database :
MEDLINE
Journal :
Science (New York, N.Y.)
Publication Type :
Academic Journal
Accession number :
4288164
Full Text :
https://doi.org/10.1126/science.154.3747.402