Light-evoked changes in chick optic lobe adenylate-cyclase.

Authors :: Nistico' G
De Sarro A
Pata P
Richetti A
Rotiroti D
Di Giorgio RM
Source :: Research communications in chemical pathology and pharmacology [Res Commun Chem Pathol Pharmacol] 1979 Apr; Vol. 24 (1), pp. 13-25.
Publication Year :: 1979
Abstract: The effects of exposure to 48 h darkness and to stroboscope stimulation on chick optic lobe adenylate-cyclase activity were studied. A significant decrease in adenylate-cyclase after 48 h exposure to darkness occurred with return to normal values after re-exposure to light. Stroboscope stimulation for 3 min produced instead a marked increase in optic lobe adenylate-cyclase. Present experiments suggest that cAMP may serve as inhibitory messenger in synaptic transmission along central visual pathways.