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[Abnormal movements induced by psychotropic drugs].
- Source :
-
L'Encephale [Encephale] 1979; Vol. 5 (1), pp. 41-8. - Publication Year :
- 1979
-
Abstract
- The abnormal movements produced by the psychotropic drugs are related to various physiopathological mechanisms: -- dopaminergic receptors blockage provokes neuroleptic parkinsoniam tremor; -- neuroleptic-induced tardive dyskinesia is similar to 1. Dopa abnormal movements; tardive dyskinesia is due to denervation induced hypersensitivity of the dopamine receptor; the 1. Dopa dyskinesia is probably related to altered responsiveness of these receptors due to an increase in dopaminergic receptor sensitivity; -- antidepressant drugs, particularly lithium, provoke tremor, alleviated by beta blockage; it is probably caused by an abnormal sensitivity of the beta noradrenergic receptors.
- Subjects :
- Chorea chemically induced
Humans
Levodopa adverse effects
Lithium adverse effects
Movement Disorders physiopathology
Parkinson Disease, Secondary chemically induced
Receptors, Dopamine drug effects
Receptors, Drug drug effects
Dyskinesia, Drug-Induced etiology
Movement Disorders chemically induced
Psychotropic Drugs adverse effects
Tremor chemically induced
Subjects
Details
- Language :
- French
- ISSN :
- 0013-7006
- Volume :
- 5
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- L'Encephale
- Publication Type :
- Academic Journal
- Accession number :
- 477589