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[Abnormal movements induced by psychotropic drugs].

Authors :
Rondot P
Bathien N
Source :
L'Encephale [Encephale] 1979; Vol. 5 (1), pp. 41-8.
Publication Year :
1979

Abstract

The abnormal movements produced by the psychotropic drugs are related to various physiopathological mechanisms: -- dopaminergic receptors blockage provokes neuroleptic parkinsoniam tremor; -- neuroleptic-induced tardive dyskinesia is similar to 1. Dopa abnormal movements; tardive dyskinesia is due to denervation induced hypersensitivity of the dopamine receptor; the 1. Dopa dyskinesia is probably related to altered responsiveness of these receptors due to an increase in dopaminergic receptor sensitivity; -- antidepressant drugs, particularly lithium, provoke tremor, alleviated by beta blockage; it is probably caused by an abnormal sensitivity of the beta noradrenergic receptors.

Details

Language :
French
ISSN :
0013-7006
Volume :
5
Issue :
1
Database :
MEDLINE
Journal :
L'Encephale
Publication Type :
Academic Journal
Accession number :
477589