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Tobramycin and gentamicin concentrations in the serum of normal and anephric patients.
- Source :
-
Antimicrobial agents and chemotherapy [Antimicrob Agents Chemother] 1973 Jan; Vol. 3 (1), pp. 125-9. - Publication Year :
- 1973
-
Abstract
- The serum half-life of tobramycin was found to be the same as that of gentamicin in patients with similar renal function. The values ranged from 2 hr in normal volunteers to 53.4 hr in anephric patients. Both drugs were readily removed from the serum by the Kiil artificial kidney, with a 70% reduction in serum concentrations during a 12-hr dialysis period.
Details
- Language :
- English
- ISSN :
- 0066-4804
- Volume :
- 3
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- Antimicrobial agents and chemotherapy
- Publication Type :
- Academic Journal
- Accession number :
- 4790568
- Full Text :
- https://doi.org/10.1128/AAC.3.1.125