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Development and testing of new hypoxic cell radiosensitizers.
- Source :
-
Radiology [Radiology] 1979 Nov; Vol. 133 (2), pp. 515-7. - Publication Year :
- 1979
-
Abstract
- Several new electron-affinic compounds have been shown to possess radiosensitizing ability in hypoxic mammalian cells. The correlation between chemical structure and biological activity can aid in the design and synthesis of new agents with potentially greater hypoxic cell radiosensitizing ability.
- Subjects :
- Animals
Cell Survival drug effects
Cell Survival radiation effects
Cricetinae
Dose-Response Relationship, Radiation
Fibroblasts drug effects
Fibroblasts radiation effects
Lung
Metronidazole pharmacology
Misonidazole pharmacology
Neoplasms drug therapy
Structure-Activity Relationship
Oxygen
Radiation-Sensitizing Agents pharmacology
Subjects
Details
- Language :
- English
- ISSN :
- 0033-8419
- Volume :
- 133
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- Radiology
- Publication Type :
- Academic Journal
- Accession number :
- 493545
- Full Text :
- https://doi.org/10.1148/133.2.515