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Studies on carbanilic acid esters of cyclic amino alcohols. 4. Esters of pyrrolidinols and piperidinols as local anesthetics.
- Source :
-
Journal of medicinal chemistry [J Med Chem] 1971 Aug; Vol. 14 (8), pp. 710-4. - Publication Year :
- 1971
- Subjects :
- Anesthesia, Epidural
Animals
Anura
Carbamates administration & dosage
Carbamates chemical synthesis
Carbamates toxicity
Chemical Phenomena
Chemistry
Cornea drug effects
Drug Synergism
Epinephrine pharmacology
Esters chemical synthesis
Esters pharmacology
Guinea Pigs
Injections, Intradermal
Injections, Intravenous
Lethal Dose 50
Male
Mice
Piperidines administration & dosage
Piperidines chemical synthesis
Piperidines toxicity
Pyrrolidines administration & dosage
Pyrrolidines chemical synthesis
Pyrrolidines toxicity
Rabbits
Rats
Sciatic Nerve drug effects
Structure-Activity Relationship
Time Factors
Anesthetics, Local chemical synthesis
Carbamates pharmacology
Piperidines pharmacology
Pyrrolidines pharmacology
Subjects
Details
- Language :
- English
- ISSN :
- 0022-2623
- Volume :
- 14
- Issue :
- 8
- Database :
- MEDLINE
- Journal :
- Journal of medicinal chemistry
- Publication Type :
- Academic Journal
- Accession number :
- 5114068
- Full Text :
- https://doi.org/10.1021/jm00290a010