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Inhibition of mitochondrial metabolism by the diabetogenic thiadiazine diazoxide. I. Action on succinate dehydrogenase and TCA-cycle oxidations.
- Source :
-
Biochemical pharmacology [Biochem Pharmacol] 1971 Jun; Vol. 20 (6), pp. 1271-80. - Publication Year :
- 1971
- Subjects :
- Acetoacetates biosynthesis
Adenosine Diphosphate pharmacology
Animals
Carbon Dioxide biosynthesis
Carbon Isotopes
Carnitine metabolism
Flavoproteins metabolism
Heart drug effects
In Vitro Techniques
Insulin metabolism
Insulin Secretion
Kinetics
Malates pharmacology
Male
Malonates pharmacology
Mitochondria, Liver drug effects
Mitochondria, Liver enzymology
Mitochondria, Muscle drug effects
Myocardium cytology
Oxygen Consumption
Palmitic Acids metabolism
Pancreas drug effects
Pancreas metabolism
Pyruvates metabolism
Rabbits
Rats
Spectrophotometry
Uncoupling Agents pharmacology
Citric Acid Cycle drug effects
Diazoxide pharmacology
Mitochondria, Liver metabolism
Mitochondria, Muscle metabolism
Myocardium metabolism
Succinate Dehydrogenase antagonists & inhibitors
Subjects
Details
- Language :
- English
- ISSN :
- 0006-2952
- Volume :
- 20
- Issue :
- 6
- Database :
- MEDLINE
- Journal :
- Biochemical pharmacology
- Publication Type :
- Academic Journal
- Accession number :
- 5118123
- Full Text :
- https://doi.org/10.1016/0006-2952(71)90358-3