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Vagal bradycardia produced by microinjections of morphine-like drugs into the nucleus ambiguus in anaesthetized dogs.
- Source :
-
European journal of pharmacology [Eur J Pharmacol] 1979 Nov 16; Vol. 59 (3-4), pp. 287-91. - Publication Year :
- 1979
-
Abstract
- The site in the dog medulla oblongata where fentanyl or met-enkephalinamide produced vagal bradycardia was determined using microinjections. The nucleus ambiguus was found to be a selective and highly sensitive area for the vagal bradycardia.
- Subjects :
- Animals
Dogs
Electric Stimulation
Enkephalins administration & dosage
Female
Fentanyl administration & dosage
Hemodynamics drug effects
Injections
Male
Microinjections
Splanchnic Nerves drug effects
Endorphins pharmacology
Enkephalins pharmacology
Fentanyl pharmacology
Heart Rate drug effects
Medulla Oblongata physiology
Vagus Nerve physiology
Subjects
Details
- Language :
- English
- ISSN :
- 0014-2999
- Volume :
- 59
- Issue :
- 3-4
- Database :
- MEDLINE
- Journal :
- European journal of pharmacology
- Publication Type :
- Academic Journal
- Accession number :
- 527649
- Full Text :
- https://doi.org/10.1016/0014-2999(79)90292-9