Back to Search
Start Over
Product inhibition of the fermentative formation of glutamic acid.
- Source :
-
Applied microbiology [Appl Microbiol] 1970 Aug; Vol. 20 (2), pp. 215-7. - Publication Year :
- 1970
-
Abstract
- The addition of penicillin to cells of Corynebacterium glutamicum growing in 5-liter fermentors initiated the excretion of glutamic acid. The rate of glutamate production in fermentors declined continuously with time and reached 75% of the initial rate in 24 hr after penicillin had been added. The addition of glutamate to resting cell suspensions had only a slight effect on sugar utilization but caused a marked decrease in glutamate excretion. It is suggested that the high level of glutamate accumulating in the fermentation broth is responsible for inhibiting its own production.
Details
- Language :
- English
- ISSN :
- 0003-6919
- Volume :
- 20
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- Applied microbiology
- Publication Type :
- Academic Journal
- Accession number :
- 5480097
- Full Text :
- https://doi.org/10.1128/am.20.2.215-217.1970