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Isolation of 2-amino-1-naphthyl hydrogen sulphate with cetylpyridinium bromide from metabolic and chemical oxidations of 2-naphthylamine.
- Source :
-
The Biochemical journal [Biochem J] 1970 Sep; Vol. 119 (3), pp. 541-6. - Publication Year :
- 1970
-
Abstract
- 1. 2-Amino-1-naphthyl hydrogen sulphate can be rapidly isolated from the urine of dogs dosed with 2-naphthylamine by precipitation with cetylpyridinium bromide. 2. No evidence was obtained for the presence of 2-naphthylhydroxylamine-O-sulphonic acid, noteworthy as a possible source of the carcinogens, 2-naphthylhydroxylamine and 2-amino-1-naphthol. 3. Treatment of neutral persulphate oxidations of 2-naphthylamine with the reagent gave only the cetylpyridinium salt of 2-amino-1-naphthyl hydrogen sulphate.
- Subjects :
- Animals
Carcinogens
Amines urine
Subjects
Details
- Language :
- English
- ISSN :
- 0264-6021
- Volume :
- 119
- Issue :
- 3
- Database :
- MEDLINE
- Journal :
- The Biochemical journal
- Publication Type :
- Academic Journal
- Accession number :
- 5500314
- Full Text :
- https://doi.org/10.1042/bj1190541