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Synthesis of ent-17-(prop-1-ynyl-17 beta-hydroxy-11 beta-(4-(N,N-dimethylamino)-phenyl)-4,9-estradien-3-one, the antipode of RU-38 486.
- Source :
-
Steroids [Steroids] 1984 Dec; Vol. 44 (6), pp. 519-30. - Publication Year :
- 1984
-
Abstract
- The title compound was synthesized and tested for its biological activities. It showed neither antiprogesterone nor antiglucocorticoid properties.
- Subjects :
- Animals
Blastocyst drug effects
Female
Glucocorticoids antagonists & inhibitors
Indicators and Reagents
Liver Neoplasms, Experimental enzymology
Magnetic Resonance Spectroscopy
Mifepristone
Optical Rotation
Rats
Rats, Inbred Strains
Stereoisomerism
Structure-Activity Relationship
Tyrosine Transaminase metabolism
Abortifacient Agents chemical synthesis
Abortifacient Agents, Steroidal chemical synthesis
Estrenes
Subjects
Details
- Language :
- English
- ISSN :
- 0039-128X
- Volume :
- 44
- Issue :
- 6
- Database :
- MEDLINE
- Journal :
- Steroids
- Publication Type :
- Academic Journal
- Accession number :
- 6152752
- Full Text :
- https://doi.org/10.1016/s0039-128x(84)80033-1