[Effect of pentamine on vascular tissue metabolism in experimental vascular pathology].

Authors :: Nikulin AA
Rachkov AK
Source :: Farmakologiia i toksikologiia [Farmakol Toksikol] 1984 Jan-Feb; Vol. 47 (1), pp. 57-63.
Publication Year :: 1984
Abstract: It has been demonstrated in experiments on cats and rabbits that a single and chronic administration of pentamine (1 mg/kg) produced a distinct variation in carbohydrate-energy metabolism in the tissue of different blood vessels, enhancing the glycolytic formation of ATP. Chronic administration of pentamine corrected metabolic disorders in rabbit vascular tissue in experimental pituitrin-induced hypertension.

Subjects :: Animals
Blood Vessels metabolism
Blood Vessels radiation effects
Cats
Drug Evaluation, Preclinical
Energy Metabolism drug effects
Female
Hypertension chemically induced
Hypertension metabolism
Male
Pituitary Hormones, Posterior pharmacology
Rabbits
Radiation Injuries, Experimental metabolism
Time Factors
Blood Vessels drug effects
Hypertension drug therapy
Quaternary Ammonium Compounds therapeutic use
Radiation Injuries, Experimental drug therapy

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