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[Phosphohexose isomerase in psoriasis].

Authors :
Vignale RA
Espasandiń J
Lasalvia E
Borras A
Source :
Medicina cutanea ibero-latino-americana [Med Cutan Ibero Lat Am] 1982; Vol. 10 (1), pp. 15-20.
Publication Year :
1982

Abstract

--The authors study in psoriasis an enzyme of the glucolytic way, the Phospho-hexose-isomerase. --They find significant high levels in blood and damaged skin, while these were "normal" in healthy skin. --Phospho-hexose-isomerase acts as a biological marker in psoriasis, and acquires the significance of an active cellular proliferation. --The highest values are those of the erythrodermaes which become normal with clinical involution. --The authors suggest that psoriasis, by an exaggerated cellular division inhibition mechanism, metabolism is deviated in order to bring the energetic elements and substrate to form the new cell. --Phospho-hexose-isomerase is not specific of the malignant process.

Details

Language :
Spanish; Castilian
ISSN :
0210-5187
Volume :
10
Issue :
1
Database :
MEDLINE
Journal :
Medicina cutanea ibero-latino-americana
Publication Type :
Academic Journal
Accession number :
6214672