Back to Search Start Over

[Synthesis of various acyclic analogs of pyrimidine nucleosides].

Authors :
Roveri P
Cavrini V
Gatti R
Source :
Il Farmaco; edizione scientifica [Farmaco Sci] 1984 Apr; Vol. 39 (4), pp. 346-52.
Publication Year :
1984

Abstract

As acyclic analogues of pyrimidine nucleosides, 1-[2-(2,3- dihydroxypropyloxy )ethyl]pyrimidines (III a-c) and 1-[[3-(2,3- dihydroxypropyloxy )-2-hydroxy]propyl]pyrimidines (III d-f) were synthesized and tested for in vitro activity against herpes simplex virus type 1. The compounds exhibited no significant antiherpetic activity.

Subjects

Subjects :
Pyrimidine Nucleosides pharmacology
Simplexvirus drug effects
Antiviral Agents chemical synthesis
Pyrimidine Nucleosides chemical synthesis

Details

Language :
Italian
ISSN :
0430-0920
Volume :
39
Issue :
4
Database :
MEDLINE
Journal :
Il Farmaco; edizione scientifica
Publication Type :
Academic Journal
Accession number :
6327364

Tools

Authors Abstract Subjects Details