Acivicin: a new glutamine antagonist in clinical trials.

Subjects

Subjects :

Animals
Antibiotics, Antineoplastic therapeutic use
Antibiotics, Antineoplastic toxicity
Antimetabolites therapeutic use
Antimetabolites toxicity
Dose-Response Relationship, Drug
Drug Evaluation
Female
Half-Life
Humans
Isoxazoles therapeutic use
Isoxazoles toxicity
Kinetics
Leukemia, Experimental metabolism
Liver Neoplasms, Experimental metabolism
Macaca mulatta
Male
Mice
Neoplasms drug therapy
Neoplasms metabolism
Purines biosynthesis
Pyrimidines biosynthesis
Sarcoma, Experimental
Antibiotics, Antineoplastic metabolism
Antimetabolites metabolism
Glutamine antagonists & inhibitors
Isoxazoles metabolism
Oxazoles metabolism

Details

Language :

English

ISSN :

0732-183X

Volume :

2

Issue :

9

Database :

MEDLINE

Journal :

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Publication Type :

Academic Journal

Accession number :

6470756

Full Text :

https://doi.org/10.1200/JCO.1984.2.9.1064