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Effect of 4-aminopyridine on gastric secretion in rats.

Authors :
Mantovani P
Taddei E
Giachetti D
Source :
Bollettino della Societa italiana di biologia sperimentale [Boll Soc Ital Biol Sper] 1984 Jul 31; Vol. 60 (7), pp. 1381-4.
Publication Year :
1984

Abstract

A study was performed in order to examine the effect of 4-Aminopyridine on gastric secretion of the rat. Acid secretion was evaluated in the stomach perfused rat preparation in anaesthetized animals. Systemic administration of the drug dose depently stimulated gastric secretion and the threshold dose was not dissimilar to that of Histamine. Atropine sulphate was able to antagonize the stimulating effect of the drug.

Details

Language :
English
ISSN :
0037-8771
Volume :
60
Issue :
7
Database :
MEDLINE
Journal :
Bollettino della Societa italiana di biologia sperimentale
Publication Type :
Academic Journal
Accession number :
6477751