[Clinical experience with an ampicillin suppository (KS-R1) in bacterial infections in children].

In order to evaluate effectiveness of ABPC suppository (KS-R1) in the treatment of bacterial infections of children, the clinical studies were carried out. KS-R1 was given in rectum to 14 patients in doses of 24.2 approximately 65.8 mg/kg (average 38.5 mg/kg) in 3 approximately 4 divided doses for 3 approximately 8 days (average 4.0 days); 6 with acute tonsillitis, 3 with pneumonia, 1 with otitis media, 4 with UTI. The overall efficacy rate was 100%. Bacterial efficacy was good, i.e. 8 of the 8 strains disappeared. Any clinical side effects and laboratory abnormalities were not observed during treatment. The above results suggested that KS-R1 is a useful antibiotics for pediatric bacterial infections.