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Hyperosmolar hyperglycemic nonketotic coma. A complication of short-term systemic corticosteroid use.
- Source :
-
Ophthalmology [Ophthalmology] 1983 Oct; Vol. 90 (10), pp. 1239-42. - Publication Year :
- 1983
-
Abstract
- Hyperosmolar hyperglycemic nonketotic coma is a serious and often lethal clinical biochemical syndrome. We report three cases of ophthalmic problems that were treated with a short course of oral corticosteroids and which resulted in the development of hyperosmolar hyperglycemic nonketotic coma. Two of these cases concerned relatively young, previously healthy patients and had fatal outcomes. The third patient, who was elderly, survived because of early detection and initiation of therapy. All three cases demonstrate that hyperosmolar hyperglycemic nonketotic coma is a serious potential complication of systemic steroidal therapy, even in a short course of treatment such as is often used in ophthalmology.
- Subjects :
- Administration, Oral
Adrenal Cortex Hormones administration & dosage
Adult
Aged
Diabetes Complications
Eye Diseases drug therapy
Female
Humans
Hyperglycemic Hyperosmolar Nonketotic Coma mortality
Hyperglycemic Hyperosmolar Nonketotic Coma physiopathology
Male
Obesity complications
Adrenal Cortex Hormones adverse effects
Diabetic Coma chemically induced
Hyperglycemic Hyperosmolar Nonketotic Coma chemically induced
Subjects
Details
- Language :
- English
- ISSN :
- 0161-6420
- Volume :
- 90
- Issue :
- 10
- Database :
- MEDLINE
- Journal :
- Ophthalmology
- Publication Type :
- Academic Journal
- Accession number :
- 6657199
- Full Text :
- https://doi.org/10.1016/s0161-6420(83)34403-1