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Ectopic hamartomatous thymoma. A distinctive benign lesion of lower neck.
- Source :
-
The American journal of surgical pathology [Am J Surg Pathol] 1984 Jul; Vol. 8 (7), pp. 501-13. - Publication Year :
- 1984
-
Abstract
- Five cases of a distinctive tumor located in the soft tissues of the lower neck in adults are described. The lesion is characterized microscopically by the presence of four components: cellular areas made up of spindle elements; epithelial islands composed of solid nests, trabeculae and cysts; mature adipose tissue; and lymphocytes, sometimes arranged in a Hassall's corpuscle-like fashion. Electron microscopy and immunostaining for keratin showed that the spindle cell component was of epithelial nature. These tumors were supraclavicular or suprasternal in location, and no local recurrence has developed in any case following local resection. We interpret these lesions as benign tumors arising on the basis of a developmental defect. We think that they are derived from the third branchial arch and that they are composed of abnormal thymic tissue.
- Subjects :
- Adult
Female
Hamartoma classification
Hamartoma embryology
Hamartoma ultrastructure
Head and Neck Neoplasms classification
Head and Neck Neoplasms embryology
Head and Neck Neoplasms ultrastructure
Humans
Male
Middle Aged
Thymoma classification
Thymoma embryology
Thymoma ultrastructure
Hamartoma pathology
Head and Neck Neoplasms pathology
Thymoma pathology
Subjects
Details
- Language :
- English
- ISSN :
- 0147-5185
- Volume :
- 8
- Issue :
- 7
- Database :
- MEDLINE
- Journal :
- The American journal of surgical pathology
- Publication Type :
- Academic Journal
- Accession number :
- 6742312