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[Current immunologic aspects of kidney transplantation].
- Source :
-
Der Urologe. Ausg. A [Urologe A] 1982 Sep; Vol. 21 (5), pp. 280-9. - Publication Year :
- 1982
-
Abstract
- The results of clinical kidney transplantation are mainly dependent on immunologic factors many of which are unknown or of unspecified importance. Blood transfusions have a favorable effect on graft prognosis, although our knowledge about optimal transfusion protocols and transfusion-induced mechanisms is still incomplete. The value of HLA-typing is controversial: whereas compatibility of the "classical" HLA-A,B,C antigens improves graft survival only moderately, HLA-DR typing, routinely performed for the last 3 years only, might be of greater importance. In addition, non-HLA systems, such as endothelial/monocytic antigens or the Lewis blood group system, appear to play a role in graft rejection. The individual immune reactivity a recipient to a large extent determines the fate of a graft. The multifactorial dependence of graft prognosis is discussed in this report.
- Subjects :
- Blood Group Incompatibility immunology
Blood Transfusion
Graft Rejection drug effects
Graft Survival
HLA Antigens immunology
Histocompatibility Testing
Humans
Immunocompetence drug effects
Immunosuppressive Agents therapeutic use
Kidney immunology
Tissue Donors
Kidney Transplantation
Transplantation Immunology drug effects
Subjects
Details
- Language :
- German
- ISSN :
- 0340-2592
- Volume :
- 21
- Issue :
- 5
- Database :
- MEDLINE
- Journal :
- Der Urologe. Ausg. A
- Publication Type :
- Academic Journal
- Accession number :
- 6758280