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Increased carbohydrate substitution of lipoteichoic acid during inhibition of protein synthesis.

Authors :
Kessler RE
Wicken AJ
Shockman GD
Source :
Journal of bacteriology [J Bacteriol] 1983 Jul; Vol. 155 (1), pp. 138-44.
Publication Year :
1983

Abstract

Decreases in electrophoretic mobilities of intracellular lipoteichoic acid, intracellular deacylated lipoteichoic acid, and extracellular deacylated lipoteichoic acid were observed during inhibition of protein synthesis in Streptococcus faecium after exposure to chloramphenicol or valine deprivation. Increased carbohydrate content, and thus an increased mass-to-charge ratio, rather than changes in ester alanine content or novel fatty acid substitutions, appeared to account for the decreased electrophoretic mobilities. The increase in carbohydrate content, as judged from mobility measurements, was progressive over time and appeared to occur on biosynthetically new lipoteichoic acid as well as on lipoteichoic acid made before inhibition of protein synthesis.

Details

Language :
English
ISSN :
0021-9193
Volume :
155
Issue :
1
Database :
MEDLINE
Journal :
Journal of bacteriology
Publication Type :
Academic Journal
Accession number :
6863217
Full Text :
https://doi.org/10.1128/jb.155.1.138-144.1983