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[Comparative study of the biological properties of influenza virus preparations purified by centrifugation and chromatography].

Authors :
Iordan AG
Mazhul' LA
Shcheglovitova ON
Ageeva ON
Source :
Voprosy virusologii [Vopr Virusol] 1983 Mar-Apr (2), pp. 150-4.
Publication Year :
1983

Abstract

A comparative study of chromatography and centrifugation as applied to purification of 2 influenza virus strains with different antigenic structure (H0N1 and H2N2) and of some biological properties of the resulting preparations was carried out. Certain strain-specific differences manifested in their chromatographic behaviour and in the degree of purification of virions from the allantoic fluid proteins were found. Some quantitative differences observed in the capacity of the resulting virus preparations to infect chick embryos and primary and continuous cells are insignificant and cannot be used for judgement of advantages of one or the other of the methods used for influenza virus purification.

Details

Language :
Russian
ISSN :
0507-4088
Issue :
2
Database :
MEDLINE
Journal :
Voprosy virusologii
Publication Type :
Academic Journal
Accession number :
6868552