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Transport mechanisms of 6-diazo-5-oxo-L-norleucine in Escherichia coli K-12.
- Source :
-
Microbiologica [Microbiologica] 1982 Jan; Vol. 5 (1), pp. 57-61. - Publication Year :
- 1982
-
Abstract
- The diazo antibiotic 6 diazo-5-oxo-L-norleucine is transported into Escherichia coli using the general aromatic amino acid transport system and a specific phenylalanine transport system. Resistance to this antibiotic is the result of a decreased rate of transport of the antibiotic and also the result of a more rapid rate of efflux of the antibiotic from the cell.
- Subjects :
- Amino Acids metabolism
Azaserine pharmacology
Biological Transport
Diazooxonorleucine pharmacology
Drug Resistance, Microbial
Escherichia coli drug effects
Escherichia coli genetics
Genes, Bacterial
Mutation
Phenylalanine metabolism
Azo Compounds metabolism
Diazooxonorleucine metabolism
Escherichia coli metabolism
Subjects
Details
- Language :
- English
- ISSN :
- 0391-5352
- Volume :
- 5
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- Microbiologica
- Publication Type :
- Academic Journal
- Accession number :
- 7050636