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Age-related variations in human lymphocyte DNA.

Authors :
Turner DR
Morley AA
Seshadri RS
Sorrell JR
Source :
Mechanisms of ageing and development [Mech Ageing Dev] 1981 Nov; Vol. 17 (3), pp. 305-9.
Publication Year :
1981

Abstract

The molecular weight of DNA from human peripheral lymphocytes has been measured on alkaline sucrose density gradients. The number average molecular weight (MN) of DNA is found to decrease as the age of the donor increases. This result is discussed with reference to lesions in DNA, both repairable and non-repairable, which may accumulate with age.

Details

Language :
English
ISSN :
0047-6374
Volume :
17
Issue :
3
Database :
MEDLINE
Journal :
Mechanisms of ageing and development
Publication Type :
Academic Journal
Accession number :
7321603
Full Text :
https://doi.org/10.1016/0047-6374(81)90068-3