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[Plasma dopamine-beta-hydroxylase activity in pheochromocytoma (author's transl)].
- Source :
-
Annales d'endocrinologie [Ann Endocrinol (Paris)] 1980 Jan-Feb; Vol. 41 (1), pp. 43-9. - Publication Year :
- 1980
-
Abstract
- In 3 patients with proved pheochromocytoma, circulating catecholamine concentrations, vanillylmandelic acid and total free catecholamine urinary excretion, dopamine-beta-hydroxylase activities in plasma were measured the day before surgery, during the removal of the tumour and postoperatively. Following the removal of the pheochromocytoma, all these parameters declined with a different rate, possibly related to the half-life proper to each molecule. The results showing a decrease in plasma D beta H activities after the removal of the tumors are in good accordance with most authors. The mechanism and the meaning of catecholamines release from non-innervated tumor-cells remain to be elucidated. By considering these three cases, it does not seem that the evolution of D beta H activity after removal of the tumor is dependent upon the fact that the pheochromocytoma releases preferentially either epinephrine or nephinephrine.
Details
- Language :
- French
- ISSN :
- 0003-4266
- Volume :
- 41
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- Annales d'endocrinologie
- Publication Type :
- Academic Journal
- Accession number :
- 7396393