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Design of phase II clinical trials in cancer using decision theory.
- Source :
-
Cancer treatment reports [Cancer Treat Rep] 1980 Feb-Mar; Vol. 64 (2-3), pp. 519-24. - Publication Year :
- 1980
-
Abstract
- An application of decision theory to the design of phase II clinical trials in cancer is presented. A risk function which depends on the prior distribution of the response rate, the costs of treating a patient, and the gains or losses resulting from the decision taken upon completion of the study is derived and optimal restricted sampling plans for a response rate of 20% are provided.
Details
- Language :
- English
- ISSN :
- 0361-5960
- Volume :
- 64
- Issue :
- 2-3
- Database :
- MEDLINE
- Journal :
- Cancer treatment reports
- Publication Type :
- Academic Journal
- Accession number :
- 7407793