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Somatic-cell hybrids producing antibodies against CEA.

Authors :
Rogers GT
Rawlins GA
Bagshawe KD
Source :
British journal of cancer [Br J Cancer] 1981 Jan; Vol. 43 (1), pp. 1-4.
Publication Year :
1981

Abstract

Monoclonal antibodies to carcinoembryonic antigen (CEA) promise improved specificity for the measurement of this widely expressed human cancer antigen. A mouse monoclonal antibody binds weakly to CEA in perchloric acid extracts of tumour but strongly to CEA similarly isolated from serum, and its spectrum of cancer detection differs from conventional antisera.

Details

Language :
English
ISSN :
0007-0920
Volume :
43
Issue :
1
Database :
MEDLINE
Journal :
British journal of cancer
Publication Type :
Academic Journal
Accession number :
7459230
Full Text :
https://doi.org/10.1038/bjc.1981.1