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Rooster comb and wattle tissues contain an anti-keratan sulfate monoclonal antibody epitope.

Authors :
Nakano T
Sim JS
Source :
Poultry science [Poult Sci] 1994 Feb; Vol. 73 (2), pp. 302-7.
Publication Year :
1994

Abstract

Glycosaminoglycan fractions isolated from either comb or wattle tissue were examined using ELISA for their antigenicities to AH12, a monoclonal antibody recognizing keratan sulfate. The results showed a positive antibody binding to a sulfated glycosaminoglycan fraction from either tissue. The treatment of the same fraction with keratan sulfate degrading enzyme, keratanase, or endo-beta-galactosidase resulted in a decrease in its antigenicity. These findings indicated the presence of AH12 epitope (keratan sulfate disaccharide) in both tissues.

Details

Language :
English
ISSN :
0032-5791
Volume :
73
Issue :
2
Database :
MEDLINE
Journal :
Poultry science
Publication Type :
Academic Journal
Accession number :
7511804
Full Text :
https://doi.org/10.3382/ps.0730302