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Thrombotic thrombocytopenic purpura: a rare late complication of allogeneic bone marrow transplantation.
- Source :
-
Haematologica [Haematologica] 1994 Jul-Aug; Vol. 79 (4), pp. 371-3. - Publication Year :
- 1994
-
Abstract
- Thrombotic thrombocytopenic purpura/hemolytic uremic syndrome (TTP/HUS) usually occurs in a setting of systemic infection or graft-versus-host reaction during the first weeks following transplant. We report a case of fatal TTP that developed eight months after allogeneic bone marrow transplantation (BMT) without any evident association with other transplantation-related complications. Conditioning chemotherapy could have induced the disorder by causing damage to the vascular endothelium. The removal of immunosuppression, including cessation of cyclosporin A (CyA), may have precipitated the disease.
Details
- Language :
- English
- ISSN :
- 0390-6078
- Volume :
- 79
- Issue :
- 4
- Database :
- MEDLINE
- Journal :
- Haematologica
- Publication Type :
- Academic Journal
- Accession number :
- 7806094