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Epstein-Barr virus in familial Hodgkin's disease.
- Source :
-
British journal of haematology [Br J Haematol] 1994 Nov; Vol. 88 (3), pp. 636-8. - Publication Year :
- 1994
-
Abstract
- Hodgkin's disease (HD) has been found to be linked to Epstein-Barr virus (EBV). Familial HD (FHD) may be related to a possible unknown agent. We have determined whether EBV small RNAs (EBERs) were found in Reed-Sternberg cells from FHD. Five families were studied for histological subtype and EBER presence. There was a striking similarity in FHD subtypes of each family and 3/11 (27%) of the cases were EBER positive. In conclusion, EBV EBERs are only infrequently found in FHD and other factors including viruses different from EBV should be further investigated in FHD.
Details
- Language :
- English
- ISSN :
- 0007-1048
- Volume :
- 88
- Issue :
- 3
- Database :
- MEDLINE
- Journal :
- British journal of haematology
- Publication Type :
- Academic Journal
- Accession number :
- 7819081
- Full Text :
- https://doi.org/10.1111/j.1365-2141.1994.tb05089.x