Leflunomide (HWA 486) and its analog suppress T- and B-cell proliferation in vitro, acute rejection, ongoing rejection, and antidonor antibody synthesis in mouse, rat, and cynomolgus monkey transplant recipients as well as arterial intimal thickening after balloon catheter injury.

Authors :: Morris RE
Huang X
Cao W
Zheng B
Shorthouse RA
Source :: Transplantation proceedings [Transplant Proc] 1995 Feb; Vol. 27 (1), pp. 445-7.
Publication Year :: 1995

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