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[A clinico-immunological analysis of clinical variants of connective tissue dysplasia].
- Source :
-
Terapevticheskii arkhiv [Ter Arkh] 1994; Vol. 66 (5), pp. 9-13. - Publication Year :
- 1994
-
Abstract
- The clinico-immunogenetic analysis of 47 patients with Marfan's syndrome and 83 patients with chest deformities combined with valvular prolapses and other connective tissues dysplasias elucidated a close relation of HLA-antigens allele variants with clinical dysplasia variants and specific immune alterations. The findings support the suggestion that clinical heterogeneity of connective tissue dysplasia forms results from their pathogenetic heterogeneity.
- Subjects :
- Adolescent
Adult
Alleles
Antibody Formation
Connective Tissue Diseases congenital
Connective Tissue Diseases genetics
Female
HLA Antigens blood
HLA Antigens genetics
Humans
Immunity, Cellular
Immunoglobulins blood
Male
Marfan Syndrome genetics
Marfan Syndrome immunology
Middle Aged
Thorax abnormalities
Connective Tissue Diseases immunology
Subjects
Details
- Language :
- Russian
- ISSN :
- 0040-3660
- Volume :
- 66
- Issue :
- 5
- Database :
- MEDLINE
- Journal :
- Terapevticheskii arkhiv
- Publication Type :
- Academic Journal
- Accession number :
- 7940354