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[A comparative evaluation of the hypoglycemic activity of acetyl-alpha-carnitine and chlorpropamide in experimental diabetes].

Authors :
Kim EK
Trevisani K
Trevisani M
Suslina ZA
Seĭfulla RD
Source :
Eksperimental'naia i klinicheskaia farmakologiia [Eksp Klin Farmakol] 1994 Jul-Aug; Vol. 57 (4), pp. 52-3.
Publication Year :
1994

Abstract

The comparison of the action shown by acetyl-alpha-carnitine and chloropropamide in rabbits with experimental diabetes has demonstrated that the former has a more pronounced hypoglycemic action. In combined administration, acetyl-alpha-carnitine substantially enhanced the effects of chloropropamide in the animals with experimental diabetes, which should be taken into account by clinicians in its use.

Details

Language :
Russian
ISSN :
0869-2092
Volume :
57
Issue :
4
Database :
MEDLINE
Journal :
Eksperimental'naia i klinicheskaia farmakologiia
Publication Type :
Academic Journal
Accession number :
7950787