[The effect of neurotropic agents on lipid peroxidation in the heart and stomach with neurogenic lesions].

Neurogenic gastric lesions in rats were induced by a combination of immobilization and 3-hour electrostimulation. Neurogenic cardiac injury in rabbits were induced by 3-hour electrical stimulation of the aortic arch. Thereafter the activation of lipid peroxidation in the stomach and heart was recorded. There was an increase in MDA levels and a decrease in antioxidative enzyme activity in the tissues and serum (catalase and superoxide dismutase). The administration of the neurotropic drugs which restore the activity of the sympathetic nervous system (L-DOPA, aethimizol, fenibut and piracetam) was shown to normalize the processes of lipid peroxidation.