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Metastatic malignant melanoma of the oral cavity. A retrospective study.

Authors :
Patton LL
Brahim JS
Baker AR
Source :
Oral surgery, oral medicine, and oral pathology [Oral Surg Oral Med Oral Pathol] 1994 Jul; Vol. 78 (1), pp. 51-6.
Publication Year :
1994

Abstract

Metastatic malignant melanoma of the oral cavity is rarely reported in the dental literature. This retrospective study identified metastatic oral lesions in 3.0% of 809 patients with melanoma treated at the National Institutes of Health between 1953 and 1989. Fifteen cases met established rigorous criteria for metastatic tumors and were reviewed for disease course and outcome. Nine white men and six white women, with an average age of 40.6 years, had cutaneous primary tumors predominantly of the trunk and head and neck region that commonly presented as moles that were enlarging, bleeding, or showing both of these signs. A mean of 4.2 years elapsed between primary tumor and oral metastasis diagnosis. Tongue, buccal mucosa, and parotid gland were the predominant oral sites. Enlarging oral masses, pigmented lesions, and nonhealing extraction sites with masses were common oral presentations. Surgery, chemotherapy, radiation therapy, and immunotherapy were used in various combinations for treatment of the primary lesion and oral metastasis. Prognosis, although poor, was highly variable.

Details

Language :
English
ISSN :
0030-4220
Volume :
78
Issue :
1
Database :
MEDLINE
Journal :
Oral surgery, oral medicine, and oral pathology
Publication Type :
Academic Journal
Accession number :
8078664
Full Text :
https://doi.org/10.1016/0030-4220(94)90117-1