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Protein tyrosine phosphatases: characterization of extracellular and intracellular domains.
- Source :
-
Current opinion in genetics & development [Curr Opin Genet Dev] 1994 Feb; Vol. 4 (1), pp. 31-9. - Publication Year :
- 1994
-
Abstract
- Protein tyrosine phosphatases (PTPs) play an important role in the regulation of cell growth and differentiation. With over 30 PTPs identified, the specific functions of these enzymes are now being addressed. The identification of extracellular domain receptor-like PTP interactions and the characterization of intracellular PTP 'targeting' domains represent recent efforts in this pursuit.
- Subjects :
- Amino Acid Sequence
Animals
Carbonic Anhydrases metabolism
Cell Adhesion Molecules metabolism
Cell Nucleus enzymology
Endoplasmic Reticulum enzymology
Extracellular Space enzymology
Humans
Intracellular Fluid enzymology
Leukocyte Common Antigens metabolism
Molecular Sequence Data
Molecular Structure
Protein Tyrosine Phosphatases genetics
Protein Tyrosine Phosphatases metabolism
Subcellular Fractions enzymology
Protein Tyrosine Phosphatases chemistry
Subjects
Details
- Language :
- English
- ISSN :
- 0959-437X
- Volume :
- 4
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- Current opinion in genetics & development
- Publication Type :
- Academic Journal
- Accession number :
- 8193537
- Full Text :
- https://doi.org/10.1016/0959-437x(94)90088-4