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GFAP-specific oligoclonal bands in the CSF of a patient with acute myelitis.
- Source :
-
Acta neurologica Scandinavica [Acta Neurol Scand] 1993 Aug; Vol. 88 (2), pp. 94-6. - Publication Year :
- 1993
-
Abstract
- The specificity for GFAP (glial fibrillary acidic protein) of oligoclonal IgG bands in the CSF of a patient with acute myelitis was demonstrated by isoelectric focusing and affinity blotting. Findings were confirmed by western blotting using a monoclonal antibody to GFAP as a reference. Immune reactions to this astrocyte protein are considered as arising secondary to spinal cord tissue lesion.
- Subjects :
- Acute Disease
Adult
Antibodies, Monoclonal immunology
Antibody Affinity immunology
Astrocytes immunology
Blotting, Western
Diagnosis, Differential
Enzyme-Linked Immunosorbent Assay
Evoked Potentials, Somatosensory
Glial Fibrillary Acidic Protein immunology
Humans
Immunoglobulin A cerebrospinal fluid
Immunoglobulin A immunology
Immunoglobulin G cerebrospinal fluid
Immunoglobulin G immunology
Magnetic Resonance Imaging
Male
Myelitis diagnosis
Myelitis physiopathology
Spinal Cord physiopathology
Spinal Cord Diseases diagnosis
Spinal Cord Diseases immunology
Spinal Cord Diseases physiopathology
Tibial Nerve
Glial Fibrillary Acidic Protein cerebrospinal fluid
Myelitis immunology
Subjects
Details
- Language :
- English
- ISSN :
- 0001-6314
- Volume :
- 88
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- Acta neurologica Scandinavica
- Publication Type :
- Academic Journal
- Accession number :
- 8213065
- Full Text :
- https://doi.org/10.1111/j.1600-0404.1993.tb04197.x