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[The effect of low and sublethal doses of ionizing radiation on the function of the spermatogenic epithelium and the yield of dominant lethal mutations in different strains of mice].
- Source :
-
Radiobiologiia [Radiobiologiia] 1993 May-Jun; Vol. 33 (3), pp. 408-14. - Publication Year :
- 1993
-
Abstract
- There was a 30% increase in spermatozoids with microheads and a 3-fold increase in "young" spermatozoids at later times after irradiation of BALB/c mice a dose of 1.0 Gy. With radiation doses of 0.1-1.0 Gy, BALB/c and CBA mice (which differ in viability of spermatogenous cells, the number of Sertoli cells and total embryonal death rate) exhibited a significant increase in the preimplantation death at the stage of spermatogonia and stem cells. The results obtained indicate reduction of the fertilizing capacity of sperm which is probably realized as dominant lethal mutations.
- Subjects :
- Animals
Dose-Response Relationship, Radiation
Epithelium radiation effects
Gamma Rays
Male
Mice
Mice, Inbred BALB C
Mice, Inbred CBA
Radiation Tolerance
Spermatogenesis genetics
Time Factors
Whole-Body Irradiation
Genes, Dominant radiation effects
Genes, Lethal radiation effects
Mutation
Spermatogenesis radiation effects
Testis radiation effects
Subjects
Details
- Language :
- Russian
- ISSN :
- 0033-8192
- Volume :
- 33
- Issue :
- 3
- Database :
- MEDLINE
- Journal :
- Radiobiologiia
- Publication Type :
- Academic Journal
- Accession number :
- 8332721