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[The effect of low and sublethal doses of ionizing radiation on the function of the spermatogenic epithelium and the yield of dominant lethal mutations in different strains of mice].

Authors :
Mamina VP
Sheĭko LD
Source :
Radiobiologiia [Radiobiologiia] 1993 May-Jun; Vol. 33 (3), pp. 408-14.
Publication Year :
1993

Abstract

There was a 30% increase in spermatozoids with microheads and a 3-fold increase in "young" spermatozoids at later times after irradiation of BALB/c mice a dose of 1.0 Gy. With radiation doses of 0.1-1.0 Gy, BALB/c and CBA mice (which differ in viability of spermatogenous cells, the number of Sertoli cells and total embryonal death rate) exhibited a significant increase in the preimplantation death at the stage of spermatogonia and stem cells. The results obtained indicate reduction of the fertilizing capacity of sperm which is probably realized as dominant lethal mutations.

Details

Language :
Russian
ISSN :
0033-8192
Volume :
33
Issue :
3
Database :
MEDLINE
Journal :
Radiobiologiia
Publication Type :
Academic Journal
Accession number :
8332721