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[The efficacy of hydroxycinnamic acids in toxic lesions of the liver].
- Source :
-
Eksperimental'naia i klinicheskaia farmakologiia [Eksp Klin Farmakol] 1993 Mar-Apr; Vol. 56 (2), pp. 55-8. - Publication Year :
- 1993
-
Abstract
- The albino rat experiments studied the pharmacological action of oxycinnamic acid derivatives in acute tetrachloromethane-induced hepatic dystrophy and combined CCl4-ethanol-induced hepatic lesion. The tested agents were found to produce cholagogic, membrane-protective, and antioxidative effects in these hepatic abnormalities, thus improving the functional (cholate- and glycogen-synthetic) parameters of the liver.
- Subjects :
- Acute Disease
Animals
Carbon Tetrachloride Poisoning complications
Carbon Tetrachloride Poisoning drug therapy
Chemical and Drug Induced Liver Injury etiology
Drug Evaluation, Preclinical
Ethanol toxicity
Flavonoids therapeutic use
Liver drug effects
Plant Extracts therapeutic use
Rats
Rats, Wistar
Vitamin E therapeutic use
Chemical and Drug Induced Liver Injury drug therapy
Coumaric Acids therapeutic use
Subjects
Details
- Language :
- Russian
- ISSN :
- 0869-2092
- Volume :
- 56
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- Eksperimental'naia i klinicheskaia farmakologiia
- Publication Type :
- Academic Journal
- Accession number :
- 8348042