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Caldesmon.
- Source :
-
Current opinion in cell biology [Curr Opin Cell Biol] 1993 Feb; Vol. 5 (1), pp. 70-6. - Publication Year :
- 1993
-
Abstract
- Recent research has led to an understanding of the in vitro properties of caldesmon, including the regulation of actomyosin ATPase activity, cross-linking between actin and myosin, enhancement of microfilament stability and stimulation of polymerization of actin. While it remains to be established whether caldesmon functions similarly in vivo, recent studies have suggested that smooth muscle caldesmon regulates the inhibition of vascular smooth muscle tone, and that non-muscle caldesmon plays roles in the regulation of cell motility and cytoskeletal organization in three biological activities: granule movement, hormone secretion and reorganization of microfilaments during mitosis.
- Subjects :
- Actin Cytoskeleton metabolism
Actins metabolism
Amino Acid Sequence
Animals
Calcium metabolism
Calmodulin-Binding Proteins chemistry
Calmodulin-Binding Proteins metabolism
Mitosis
Molecular Sequence Data
Molecular Weight
Muscle, Smooth metabolism
Myosins antagonists & inhibitors
Organ Specificity
Phosphorylation
Pituitary Gland, Anterior metabolism
Calmodulin-Binding Proteins physiology
Subjects
Details
- Language :
- English
- ISSN :
- 0955-0674
- Volume :
- 5
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- Current opinion in cell biology
- Publication Type :
- Academic Journal
- Accession number :
- 8448032
- Full Text :
- https://doi.org/10.1016/s0955-0674(05)80010-9