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Encephalopathy associated with bismuth subgallate therapy.
- Source :
-
Clinical neuropharmacology [Clin Neuropharmacol] 1993 Apr; Vol. 16 (2), pp. 173-6. - Publication Year :
- 1993
-
Abstract
- A 74-year-old man developed paranoid ideation, memory impairment, and defective gustatory and olfactory function while on bismuth subgallate therapy for use as a colostomy deodorant. Twenty-four-hour urine bismuth was elevated at 889 micrograms/day, and whole blood bismuth concentration was 67 micrograms/L. The patient improved after discontinuation of bismuth subgallate; there was resolution of paranoid behavior and gustatory and olfactory functions improved. Follow-up whole blood bismuth concentration was 21 micrograms/L 4 weeks after cessation. Altered gustatory and olfactory function have not been previously reported with bismuth intoxication.
- Subjects :
- Aged
Diabetes Complications
Gallic Acid adverse effects
Humans
Magnetic Resonance Imaging
Male
Psychiatric Status Rating Scales
Sensation Disorders chemically induced
Smell drug effects
Taste drug effects
Anti-Infective Agents adverse effects
Gallic Acid analogs & derivatives
Mental Disorders chemically induced
Organometallic Compounds adverse effects
Subjects
Details
- Language :
- English
- ISSN :
- 0362-5664
- Volume :
- 16
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- Clinical neuropharmacology
- Publication Type :
- Academic Journal
- Accession number :
- 8477413
- Full Text :
- https://doi.org/10.1097/00002826-199304000-00010