Back to Search
Start Over
Functional connectivity in the motor cortex of resting human brain using echo-planar MRI.
- Source :
-
Magnetic resonance in medicine [Magn Reson Med] 1995 Oct; Vol. 34 (4), pp. 537-41. - Publication Year :
- 1995
-
Abstract
- An MRI time course of 512 echo-planar images (EPI) in resting human brain obtained every 250 ms reveals fluctuations in signal intensity in each pixel that have a physiologic origin. Regions of the sensorimotor cortex that were activated secondary to hand movement were identified using functional MRI methodology (FMRI). Time courses of low frequency (< 0.1 Hz) fluctuations in resting brain were observed to have a high degree of temporal correlation (P < 10(-3)) within these regions and also with time courses in several other regions that can be associated with motor function. It is concluded that correlation of low frequency fluctuations, which may arise from fluctuations in blood oxygenation or flow, is a manifestation of functional connectivity of the brain.
- Subjects :
- Acoustic Stimulation
Adult
Brain metabolism
Cerebrovascular Circulation
Electroencephalography
Female
Fingers physiology
Hand physiology
Humans
Male
Motor Cortex metabolism
Motor Skills
Movement
Neurons physiology
Oxygen blood
Photic Stimulation
Psychomotor Performance
Somatosensory Cortex metabolism
Somatosensory Cortex physiology
Brain physiology
Echo-Planar Imaging
Magnetic Resonance Imaging methods
Motor Cortex physiology
Rest
Subjects
Details
- Language :
- English
- ISSN :
- 0740-3194
- Volume :
- 34
- Issue :
- 4
- Database :
- MEDLINE
- Journal :
- Magnetic resonance in medicine
- Publication Type :
- Academic Journal
- Accession number :
- 8524021
- Full Text :
- https://doi.org/10.1002/mrm.1910340409