A randomized, double-blind, placebo-controlled study to determine safety, tolerance, and preliminary pharmacokinetics of ascending single doses of orally administered sirolimus (rapamycin) in stable renal transplant recipients.

Subjects

Subjects :

Adult
Aged
Azathioprine therapeutic use
Cyclosporine therapeutic use
Dose-Response Relationship, Drug
Double-Blind Method
Drug Therapy, Combination
Female
Humans
Immunosuppressive Agents adverse effects
Male
Middle Aged
Placebos
Polyenes adverse effects
Prednisolone therapeutic use
Sirolimus
Immunosuppressive Agents pharmacokinetics
Immunosuppressive Agents therapeutic use
Kidney Transplantation immunology
Polyenes pharmacokinetics
Polyenes therapeutic use

Details

Language :

English

ISSN :

0041-1345

Volume :

28

Issue :

2

Database :

MEDLINE

Journal :

Transplantation proceedings

Publication Type :

Academic Journal

Accession number :

8623489