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Aggression and personality: association with amino acids and monoamine metabolites.
- Source :
-
Psychological medicine [Psychol Med] 1996 Mar; Vol. 26 (2), pp. 323-31. - Publication Year :
- 1996
-
Abstract
- Associations in 52 normal individuals were examined between plasma and cerebrospinal fluid (CSF) concentrations of tryptophan (Trp) and tyrosine, and concentrations of monoamine metabolites in the CSF, and scores on an aggression questionnaire, the Kinsey Institute Reaction List II, and the Eysenck Personality Questionnaire. There was a significantly positive correlation between CSF 5-hydroxyindoleacetic acid (5-HIAA) levels and extroverted aggression scores, and a significantly negative correlation between CSF 5-HIAA levels and introverted aggression scores. Males showed higher plasma Trp concentrations than females, and significantly positive correlations between plasma Trp concentrations and scores on extroverted aggression and the Eysenck E scale. Males, furthermore, showed a significantly negative correlation between CSF Trp levels and scores on the Eysenck P scale, and a significantly positive correlation between concentrations of 3-methoxy-4-hydroxy-phenylglycol in CSF and scores on moral aggression. These results suggest that central serotonin influences aggression in normal individuals through effects on personality.
- Subjects :
- Adult
Aged
Aged, 80 and over
Aggression psychology
Antisocial Personality Disorder diagnosis
Antisocial Personality Disorder psychology
Blood-Brain Barrier physiology
Brain physiopathology
Extraversion, Psychological
Female
Homovanillic Acid cerebrospinal fluid
Humans
Hydroxyindoleacetic Acid cerebrospinal fluid
Male
Methoxyhydroxyphenylglycol cerebrospinal fluid
Middle Aged
Reference Values
Serotonin physiology
Tryptophan cerebrospinal fluid
Tyrosine cerebrospinal fluid
Aggression physiology
Amino Acids cerebrospinal fluid
Antisocial Personality Disorder physiopathology
Neurotransmitter Agents cerebrospinal fluid
Personality Inventory statistics & numerical data
Subjects
Details
- Language :
- English
- ISSN :
- 0033-2917
- Volume :
- 26
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- Psychological medicine
- Publication Type :
- Academic Journal
- Accession number :
- 8685288
- Full Text :
- https://doi.org/10.1017/s0033291700034711