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[Features of vitamin D3 metabolism in liver cells in experimental diabetes mellitus].
- Source :
-
Ukrainskii biokhimicheskii zhurnal (1978) [Ukr Biokhim Zh (1978)] 1996 Jan-Feb; Vol. 68 (1), pp. 66-72. - Publication Year :
- 1996
-
Abstract
- The uptake of vitamin D3 by the liver cells and its hydroxylation in the hepatocytes of rats at experimental diabetes has been studied. It is proved that in this pathology the disturbances of vitamin D3 exchange in the rat liver take place. It is concluded that the lowering of the level of absorption of vitamin D3 by hepatocytes and its transportation to these cells from reticulocytes as well as the inhibition of vitamin D3-25-hydroxylase liver systems can be the most probable cause of these disturbances.
- Subjects :
- Absorption
Animals
Biological Transport
Cholestanetriol 26-Monooxygenase
Diabetes Mellitus, Experimental pathology
Female
Hydroxylation
Liver pathology
Rats
Rats, Wistar
Reticulocytes metabolism
Steroid Hydroxylases antagonists & inhibitors
Cholecalciferol metabolism
Diabetes Mellitus, Experimental metabolism
Liver metabolism
Subjects
Details
- Language :
- Russian
- ISSN :
- 0201-8470
- Volume :
- 68
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- Ukrainskii biokhimicheskii zhurnal (1978)
- Publication Type :
- Academic Journal
- Accession number :
- 8755104