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Distribution of thromboxane A2 receptor mRNA along the mouse nephron segments.
- Source :
-
Biochemical and biophysical research communications [Biochem Biophys Res Commun] 1996 Sep 24; Vol. 226 (3), pp. 613-7. - Publication Year :
- 1996
-
Abstract
- Thromboxane A2 (TXA2) receptor mRNA was semi-quantitated in microdissected mouse nephron segments by reverse transcription-polymerase chain reaction (RT-PCR). TXA2 receptor mRNA was most abundantly expressed in the glomerulus, followed by the distal convoluted tubule > proximal tubule, thick ascending limb of Henle, and outer medullary collecting duct. These results suggest the potential physiological roles of TXA2 in the entire renal tubule as well as in the glomerulus.
- Subjects :
- Actins biosynthesis
Animals
Blotting, Southern
DNA Primers
Dissection methods
Kidney Glomerulus metabolism
Kidney Medulla metabolism
Kidney Tubules, Collecting metabolism
Kidney Tubules, Distal metabolism
Kidney Tubules, Proximal metabolism
Loop of Henle metabolism
Male
Mice
Mice, Inbred ICR
Nephrons anatomy & histology
Nephrons physiology
Organ Specificity
Polymerase Chain Reaction methods
RNA, Messenger analysis
Receptors, Thromboxane genetics
Receptors, Thromboxane physiology
Nephrons metabolism
RNA, Messenger biosynthesis
Receptors, Thromboxane biosynthesis
Subjects
Details
- Language :
- English
- ISSN :
- 0006-291X
- Volume :
- 226
- Issue :
- 3
- Database :
- MEDLINE
- Journal :
- Biochemical and biophysical research communications
- Publication Type :
- Academic Journal
- Accession number :
- 8831666
- Full Text :
- https://doi.org/10.1006/bbrc.1996.1404