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Primary systemic allergy to human insulin: recurrence of generalized urticaria after successful desensitization.
- Source :
-
Allergy [Allergy] 1995 Dec; Vol. 50 (12), pp. 984-7. - Publication Year :
- 1995
-
Abstract
- Primary systemic allergy to human insulin is rare. We report a case of recurrent immediate local reactions followed eventually by generalized urticaria to recombinant human insulin (Humulin) in an insulin-dependent diabetic. Skin test to Humulin R was positive, and the patient was successfully desensitized using a modified rapid desensitization protocol. Two weeks later, he had another episode of generalized urticaria after Humulin R injection. His treatment was resumed at a lower dose, and within a week he was able to tolerate his usual regimen of insulin. To our knowledge, this is the first report of a recurrence of systemic reaction after successful desensitization.
Details
- Language :
- English
- ISSN :
- 0105-4538
- Volume :
- 50
- Issue :
- 12
- Database :
- MEDLINE
- Journal :
- Allergy
- Publication Type :
- Academic Journal
- Accession number :
- 8834829
- Full Text :
- https://doi.org/10.1111/j.1398-9995.1995.tb02512.x