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beta-Thalassemia mutation at -90C-->T impairs the interaction of the proximal CACCC box with both erythroid and nonerythroid factors.
- Source :
-
Blood [Blood] 1996 Oct 15; Vol. 88 (8), pp. 3248-9. - Publication Year :
- 1996
- Subjects :
- Base Sequence
Chloramphenicol O-Acetyltransferase biosynthesis
Chloramphenicol O-Acetyltransferase genetics
DNA genetics
Erythroid Precursor Cells metabolism
Genes, Reporter
Globins biosynthesis
HeLa Cells
Humans
Kruppel-Like Transcription Factors
Organ Specificity
Protein Binding
Recombinant Fusion Proteins biosynthesis
Recombinant Fusion Proteins genetics
Zinc Fingers
beta-Thalassemia ethnology
DNA metabolism
DNA-Binding Proteins metabolism
Gene Expression Regulation
Globins genetics
Point Mutation
Promoter Regions, Genetic
Transcription Factors metabolism
Transcription, Genetic
beta-Thalassemia genetics
Subjects
Details
- Language :
- English
- ISSN :
- 0006-4971
- Volume :
- 88
- Issue :
- 8
- Database :
- MEDLINE
- Journal :
- Blood
- Publication Type :
- Report
- Accession number :
- 8874232