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Blood clotting activation during normal pregnancy.
- Source :
-
Thrombosis research [Thromb Res] 1996 Nov 01; Vol. 84 (3), pp. 199-202. - Publication Year :
- 1996
-
Abstract
- Pregnancy is considered as a hypercoagulable state and an increased incidence of thromboembolic phenomena has been reported in pregnant women. Relevant changes in the hemostatic mechanism have been reported during physiological pregnancy: briefly, increased levels of coagulation factors, enhanced thrombin generation and suppression of fibrinolysis are commonly found in women with uncomplicated pregnancy. We recently described progressive increases in fibrinogen and D-dimer plasma levels during normal pregnancy. The increase in D-dimer levels makes difficult their interpretation for the exclusion of thromboembolic phenomena in pregnancy. The behavior of prothrombin fragment 1+2 (F1+2) levels during physiological pregnancy is scarcely known. The aim of this preliminary study was to establish range values of F1+2 plasma levels for different periods of normal pregnancy.
Details
- Language :
- English
- ISSN :
- 0049-3848
- Volume :
- 84
- Issue :
- 3
- Database :
- MEDLINE
- Journal :
- Thrombosis research
- Publication Type :
- Academic Journal
- Accession number :
- 8914219
- Full Text :
- https://doi.org/10.1016/0049-3848(96)00176-4